Level of evidence | Study design |
| I | Evidence obtained from a systematic review of all relevant randomised controlled trials
|
| II | Evidence obtained from at least one properly-designed randomised controlled trial
|
| III-1 | Evidence obtained from well-designed pseudo-randomised controlled trials (alternate allocation or some other method)
|
| III-2 | Evidence obtained from comparative studies (including systematic reviews of such studies) with concurrent controls and allocation not randomised, cohort studies, case-control studies, or interrupted time series with a control group
|
| III-3 | Evidence obtained from comparative studies with historical control, two or more single arm studies, or interrupted time series without a parallel control group
|
| IV | Evidence obtained from case series, either post-test or pre-test/post-test
|