current research and information 1

HIV and AIDS Information
current research and information - page 1

General information

Antiretroviral Treatment in Adult HIV Infection

HIV Antiretroviral Drug Resistance Testing

General Information

www.aidsinfo.nih.gov
This website provides a large number of articles on most aspects of HIV.

Antiretroviral Treatment in Adult HIV Infection

Antiretroviral therapy has progressed rapidly over the past decade and has achieved remarkable reductions in HIV-related mortality in most developed countries with ready access to drugs. The pace of change is so great that treatment guidelines require frequent revision.

A recently-published set of guidelines provides up-to-date recommendations. The article was convened by the USA Department of Health and Human Services (DHHS):

Go to Guidelines for Using Antiretroviral Agents among HIV-infected Adults and Adolescents: the Panel on Clinical Practices for HIV.

Current reccomended Antiretroviral treatment - Adult and adolescent guidelines are available at the www.aidsinfo.nih.gov site in PDF format.

HIV Antiretroviral Drug Resistance Testing

Despite the increasing number of antiretoviral (ARV) agents to treat HIV infection, treatment failure is still occurring. Although there are many contributing factors to treatment failure, resistance of HIV to ARV therapy is of major importance. The following websites provide up-to-date information:

www.iasusa.org/resistance_mutations/index.html
The International AIDS Society-USA's frequently-updated listing of resistance mutations and their effects.

hivdb.stanford.edu
Stanford HIV RT and Protease Sequence Database. This research-oriented site currently offers beta-test software that allows uploading of a sequence text file to a drug resistance interpretation algorithm.

hivinsite.ucsf.edu/InSite.jsp?page=li-04-25
HIV InSite. This page provides links to several resistance-related sites including some commercial sites.

www.nrl.gov.au
National Serology Reference Laboratory. This site provides the current algorithm for resistance mutation interpretation used by Australian and New Zealand laboratories involved in the 'Can Resistance Enhance Selection of Therapy' (CREST) study.